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High Fructose Corn Syrup May Fuel Colon Cancer

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It’s no secret that health experts and nutritionists have been wary of high fructose corn syrup for years. But now they have one more reason to advocate against it: a new study published in the journal Science says that the sugary substance boosts the growth of cancerous tumors in mice.

The study, conducted by researchers at Cornell University and Baylor University, found that consuming a modest amount of high-fructose corn syrup every day—about the equivalent of drinking one can of soda—can accelerate the growth of cancerous tumors in mice’s intestines.

As part of the research trial, scientists generated mice with early-stage colon cancer. Then, the scientists gave the mice a moderate amount of sweetened water, with 25% high fructose corn syrup, each day. The amount was a modest amount, meant to mimic a human’s daily consumption of one can of sugary soda. After two months, the mice developed tumors that were higher-grade and larger in size than those mice treated with only water.

Scientists say that the results suggest that even moderate amounts of high fructose corn syrup can boost the growth of early-stage tumors in the intestines. Early stage tumors can occur in young adult humans without notice, but it typically takes 20-30 years for those small, benign tumors to develop into aggressive cancer. Although further studies are necessary to determine how these findings would translate to the human body, the scientists’ ultimate findings suggest that chronic consumption of high fructose corn syrup can shorten the time it takes for intestinal cancer to develop.

High fructose corn syrup has been around—and in our food—for years. The sweeter is commonly found in processed foods like candies and soda, but over the years it has found more and more ways to creep into Americans’ meals.

As the prevalence of high fructose corn syrup has grown, so too have our waistlines. The obesity rate of America is increasing, alongside high blood pressure issues and weight-related diseases like type-2 diabetes. There have been numerous studies showing the link between consuming sugary drinks and other foods with high fructose corn syrup, and therefore the scientific and medical community’s thought on the substance was focused on its effect on obesity and obesity-related diseases.

Doctors were also aware that obesity, in turn, increases the risk of many types of cancer, such as colon cancer. But this study takes the warnings to a new level, establishing a direct causal link between the consumption of high fructose corn syrup and cancer. Researchers believe that these results may explain the correlation between an increased consumption of sugary drinks and other high-sugar processed foods over the last 30 years with an increase in colorectal cancers in adults.

But the study isn’t all bad news: it also discovered the biological mechanism that helped caused the cancerous growth enhanced by the high fructose corn syrup. The researchers focused on two enzymes: KHK, an enzyme used to metabolize fructose, and FASN, which helps the body synthesize fatty acids. Mice in the study that lacked either of these two particular enzymes did not develop larger tumors, even when fed the same amounts of high fructose corn syrup.

This discovery could help researchers and doctors better understand how cancers develop and lead to new treatments, by focusing on cancer therapies targeting the metabolism of fructose through these two
enzymes.

Additional studies, particularly those focusing on the impact on the human body, will certainly follow. But in the meantime, health experts say this is just one more reason to cut out high fructose corn syrup from your diet.

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Defective EpiPens Increase Risk of Death

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The US Food and Drug Administration announced that certain EpiPens may fail to work correctly for allergic reactions. This includes the Ep
iPen 0.3 mg and EpiPen Jr 0.15 mg and generic versions of the products.

EpiPen Malfunction

According to the FDA, the EpiPens may delay injection of the epinephrine being given for a severe allergic reaction. They may also activate too soon if the safety release is removed from the side. The correct way to remove the blue safety release is to pull it straight up with one hand while holding the pen with the other. If the person attempts to hold it and remove the release with the same hand, it may activate the medicine.

The blue safety release may already be partially raised on some of the EpiPens. This would allow the device to activate before it should, which means the person wouldn’t receive the medication for the reaction.

Another issue with the devices is that some may fail to slide out of the carrier. Other user errors could cause the EpiPens not to work correctly. The FDA recommended that patients review the instructions that come with the EpiPen periodically to ensure they know what to do in an emergency.

Pharmacists should inspect the EpiPens before they are distributed to the patient. If a patient has a device and they are having an issue with it, they can contact the manufacturer at 800-796-9526 for a replacement at no cost to them.

What EpiPens Do

EpiPens contain epinephrine, which is a medication designed to open the airways in the lungs and narrow blood vessels. It works by injection to take effect immediately.

The medication can stop wheezing, bring up severely low blood pressure and stop hives and itching as well as other symptoms of an allergic reaction. The reactions may be caused by an allergy to foods, drugs, insect bites or stings and even anaphylaxis caused by exercise. It can be given by the person suffering from the reaction and is generally kept on hand for anyone with a history of severe reactions to allergens.

The EpiPen Auto-Injector is designed for people who weigh at least 66 pounds. The EpiPen Jr Auto—Injector is prescribed for those who weight at least 33 pounds but no more than 66 pounds.

It’s important to contact a doctor after using the EpiPen even if the symptoms of the allergic reaction wear off. The EpiPen only lasts for about 30 minutes, and the person may start to have a reaction again.

Anyone who has an EpiPen should review the information and make sure they understand how it works. If they don’t, they can ask their pharmacist or doctor for information. They should also check the device to see if it is working correctly. If not, it should be replaced. It can be life-threatening to rely on the EpiPen when a person is having an episode and not have it work correctly or fail to dispense the medication at all.

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Health Concerns Over Vaping Limit Juul’s Expansion in Global Markets

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In 2019, a mysterious lung illness was linked to vaping, and several people died while thousands were diagnosed and treated. JUUL, one of the manufacturers of vaping devices, has seen more restrictions in the US because of the situation. To continue to be successful, JUUL has looked at expanding globally where fewer restrictions make it easier for vaping devices to gain new users.

Going Global

JUUL has looked at moving into several global markets in the past year. Following the strategy employed by cigarette companies, JUUL saw potential to win new consumers around the world with its vaping devices, especially after flavored devices were banned in the US.

While the company began its plan for expansion, many of these plans have been thwarted. JUUL was removed from the China market just four days after entry. Other markets that have proven fruitless include Thailand, India, Singapore, Philippines, Laos and Cambodia. JUUL has also delayed a launch in the Netherlands and stopped sales in Israel.

It appeared that South Korea would be a legitimate market for the manufacturer with a third of the men smoking and many consumers interested in the latest in Western technology and goods. JUUL started out with fast growth in the country and soon became a top brand for vaping products.

Two issues plagued JUUL in this lucrative market. First, a tax on e-liquid products made vaping devices expensive. Second, the amount of nicotine allowed in these devices is just one percent, which is less than the three and five percent that had been allowed in JUUL’s products in the US. A warning from the South Korea government about damage to the lungs from vaping products add to the problems for the vaping manufacturer.

Vaping Illness Casts Black Cloud on JUUL

Even though JUUL products aren’t linked to the lung illness, it has had an adverse effect on the company’s ability to enter global markets. Sales dropped dramatically in South Korea as the entire vaping industry was hard hit with a reduction of 90 percent in sales in the fourth quarter of 2019.

While JUUL products began to be sold in India in 2018, an official launch was planned for late 2019. India banned all e-cigarettes in the country before the launch could happen. In Indonesia, JUUL became quite popular with the younger crowd. While JUUL tried to make its products appeal as devices to help smokers stop smoking, the real use for the product came from those who both smoked and vaped as well as those who had never smoked.

While JUUL pulled out of Indonesia, many people are concerned that sales will just move online. Experts say that it’s already a flourishing market.

The illnesses in the US that were linked to vaping has led to concern around the world. Many countries that before were quite lenient with vaping have now taken action to limit or even ban the products. JUUL’s strategy to expand around the world has been delayed at least if not completed altered.

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Vaping Could Increase Health Risk with COVID-19

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The US Centers for Disease Control and Prevention has issued recommendations for those who are elderly and people who are high-risk for dealing with COVID-19. Another group who may be at risk for this disease is anyone who smokes or vapes.

Vaping Illnesses

Vaping has already been tied to a serious lung illness with many cases diagnosed and treated from the summer of 2019. Like the vaping illness, COVID-19 attacks the lungs, which could leave those who are smoking or vaping even more susceptible.

The illness tied to vaping results in permanent damage to the lungs. Many of patients have gone to the emergency room and even been put on ventilators to help with breathing because of the severity of the situation. Several have died from the disease. Those who vape may also suffer more serious effects of any illness, including flu. The issue becomes even more frightening with COVID-19.

When a person vapes, it impacts their lungs. The lungs have more difficulty clearing out foreign substances and working at normal capacity. Some experts are wondering if vaping has contributed to the number of younger people being hospitalized for the virus. A study done in China shows that people who smoke have a 14 times greater chance of developing a severe case of COVID-19 than someone who doesn’t. These same people have a 14 percent higher chance of getting pneumonia.

Along with people who smoke and vape, anyone abusing drugs could also be at an increased risk. Many of these drugs have a negative effect on the respiratory system. Opioids slow down the breathing rate, which makes it more difficult to get enough air and to send enough oxygen to the organs. Opioid misuse is already linked to an increased death rate in people who are diagnosed with respiratory issues. For many drug users, they double their risk because they also smoke or vape.

Fatalities with Vapers

With the vaping illness, many people went to the emergency room because they couldn’t breathe. The most serious cases would be put on a ventilator, and many died from the disease. The issues are similar with COVID-19. It can start with a cough and fever, but it can quickly lead to shortness of breath and pneumonia. Doctors are concerned with the need for ventilators for those who have underlying conditions or are at a higher risk. Thousands of people have already died from this virus, and vapers and smokers most likely will end up with a higher fatality rate if they are exposed.

While there were some similarities on cases involving the vaping-related lung disease, no single cause was found. Many experts and agencies recommended that people stop vaping or at least not buy vaping products from off the street because they might not know what ingredients were included. With the virus running rampant throughout the US, most experts would agree to stop vaping regardless of what products are being used.

The single best thing that anyone can do to avoid complications with the virus is to reduce their risk. That means stop smoking or vaping.

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