It is now possible to discover the presence of cancerous cells throughout the body in just ten minutes, according a recent study. Researchers from the University of Queensland in Australia have developed a special test which can show results after 10 minutes.
The researchers found out that cancer develops a distinct DNA structure when the cells are put in water. The test which has recently been developed is able to locate that structure anywhere in a person’s body. When the test is used, it is possible that cancer can be detected earlier than through current methods.
According to Professor Matt Trau, the discover that DNA molecules which are determined to be cancerous have a unique 3D nanostructure from normal DNA is a major breakthrough. It provides the ability to detect cancer in a non-invasive way from any tissue, including blood.
Portable detection devices which are relatively inexpensive have been developed to be used as diagnostic equipment, maybe even with a smartphone. The focus on early detection is nothing new. Scientists have researched methods for earlier diagnosis because it is known to improve the success rate of treatment.
Researchers from John Hopkins University made the announcement that they had developed CancerSEEK, which is a blood test able to screen for eight different types of cancer. It identifies cancer proteins in samples of blood along with other gene mutations. However, more research is needed before the test will be used throughout the medical community.
How the 10-Minute Test Works
Even with the positive news on the 10-minute test in Australia, it has not been used on humans. Major clinical trials will be necessary before it can be used on potential patients.
The signs are positive based on research that has been completed. Tests were conducted on more than 200 samples of blood and tissue. Cancerous cells were detected with an accuracy rate of 90 percent. At this time, the test has only been used in detecting prostate, breast, bowel and lymphoma cancers. The researchers believe it can be expanded to include other types of cancer as well.
Researchers have looked for a common thread among the types of cancer so a diagnostic tool could be developed that would work for every type. Cancerous cells alter the DNA of cells that would otherwise be healthy. The test can recognize this change in pattern when the cells are placed in a solution like water.
In the research, the cancerous fragments became three-dimensional structures when placed in water as viewed under a high-resolution microscope. The difference was easily recognizable compared to healthy cells placed in water.
Gold particles are used in the test because they bind with the DNA affected by cancer. The result is visible color alterations. The next step will be to develop clinical studies to determine how early cancer can be diagnosed using this test. They will also be looking at whether the test will predict the effectiveness of certain treatments. Other bodily fluids may be used to detect cancer types from the earliest to the later stages.
New Approved Treatment Becomes Available for Mesothelioma
A new treatment for patients diagnosed with mesothelioma has recently been approved by the FDA and is now available at the West Cancer Center in Memphis, TN. This is the first center in the nation to use electric therapy treatment for these patients.
An Exciting New Treatment
Electric therapy treatment works by sending electric fields into the body to target cancerous cells. The technician applies three pads to the front and back of the patient. Once the unit is turned on, electric fields are sent through the person’s body to disrupt the growth of the cancerous cells. At the same time, it leaves the healthy cells alone.
The new treatment promises to be popular because it’s not invasive. There are few side effects as well. The first patient has received the treatment, and they are wearing it for 18 hours each day. It is expected to have 97 percent control in the first year. If the patient uses the treatment along with chemotherapy, they may have a stable disease or positive response.
The device was first introduced in 2015 to treat brain tumors. It has since been used with ovarian and pancreatic cancer. It’s not being labeled as a cure, but it does help patients live longer. People diagnosed with mesothelioma normally have about two years life expectancy because this is an aggressive cancer. It’s rare, which makes research and treatment difficult.
Before the new treatment was approved, there were three options for treating mesothelioma, which included surgery, chemotherapy and radiation.
What is Mesothelioma?
Mesothelium is the tissue in the lining of your lungs, heart, stomach and other organs. Mesothelioma is a cancer of that tissue. It generally starts in the lungs, but it can begin in other organs as well. This condition has been linked to exposure to asbestos because the asbestos fibers get in the lungs when inhaled where they can’t disappear. Over time with constant exposure, more fibers get into the lungs. Symptoms of this disease often wait 20 or 30 years after exposure to show up. It starts with shortness of breath or pain in the chest. Fluid begins to accumulate, making it even more difficult to breathe.
Anyone who has been exposed to asbestos is at greater risk for developing mesothelioma. Even if you live with someone who works in the industry around asbestos can have an increased risk because they can inhale the fibers from that person’s clothing.
This type of cancer usually isn’t diagnosed until it’s advanced. The doctor will often order an X-ray of the chest or CT scan. If abnormalities are found, a biopsy may be ordered. After it has been analyzed, the results will tell if it is cancerous. Diagnosis could happen much more quickly if the person knows they were exposed to asbestos, but many people don’t think about these details of a job from 20 or 30 years ago.
Mesothelioma patients may find new hope with the treatment if it enhances the quality and quantity of their lives.
Hernia Mesh Defective Products Cause Lifelong Complications
Hernia mesh products have been around since the 1950s when they were first developed. They have become widely accepted as a method to repair hernias. Over time, manufacturers have altered these products with new materials, various coatings and unique features. Some of the mesh products have been proven to be defective, even to the point of causing life-changing injuries.
Multiple Defective Products
Even though hernia mesh products have been around for decades, new products are continually being introduced and not all of them are safe. Some of these products contain different materials and have not been tested thoroughly to determine safety. Often, additional surgery is required to remove the mesh and to repair the hernia again that the first mesh failed to treat.
Some of the products involved in lawsuits include the following:
- Covidien – one of the most recognizable names, Covidien has had numerous claims against its products. Parietex hernia mesh was one product that used the material polyester rather than polypropylene. While it tried to fix the problems associated with this product, it did not test the safety of the mesh before putting it on the market.
- Bard – another well-known name, Bard has a product called Sepramesh IP Composite, which is supposed to incorporate itself into the tissue and is made with polyglycolic acid and polypropylene. It is used in reconstructing soft tissue loss, but has been associated with serious side effects, including bowel obstruction and adhesions, which often require surgeries to correct.
- Ethicon – the Ethicon Physiomesh was approved by the Food and Drug Administration (FDA) in April 2010 and launched as a product in October 2010. However, it was taken off the market voluntarily because of issues with the base layer, which is made of polypropylene. This plastic material is coated with polymeric films which is supposed to cause the material to degrade, but it often remains in the person’s body for a long time.
- Atrium – The Atrium C-QUR was approved for use by the FDA in March 2006, but it has been associated with problems. Two versions, one used for pre-peritoneal repairs and another with placement in the intra-abdominal area, were designed for small hernia issues.
Complications from Hernia Mesh Products
Hernia mesh products can cause a wide range of side effects. The most minor include severe pain, but most require surgery to fix the problem. The most common complications from this product is also the most serious. Adhesion and bowel obstruction are common along with the risk of rejection, migration and infection.
One of the most common complications is adhesion which causes scar-like tissue to stick together and results in chronic pain that may be severe. It can lead to bowel obstruction which can be life-threatening.
In one case, a hernia mesh product attached to the small intestine of a patient. It was necessary to remove the mesh just 12 days after the original surgery to implant it. The mesh products are usually coated to prevent the risk of adhesion, but the coating is dissolved in the body in a short time, which then allows the product to adhere to the intestines or other tissue.
The mesh can also migrate to other areas of the body, where it can cause other issues. One of the most severe and dangerous complications is bowel obstruction. The person begins to feel nauseated and vomits and is unable to pass stool or even gas. Treatment is necessary immediately or the person can die. The obstruction will cut off blood flow if not treated quickly, which will allow part of the intestine to die and need to be removed. According to the FDA, a major reason for bowel obstruction is due to recalled mesh.
Bowel perforation is another serious condition which happens from hernia mesh. It occurs when the product punctures the bowel. The mesh can also perforate other organs or the abdominal wall. Symptoms include nausea and vomiting, severe pain in the abdomen and rigidity. Bacteria gets into the abdominal cavity and leads to peritonitis or sepsis and requires immediate medical attention.
These and other complications may occur right away after the initial surgery. However, it can also be years before a person experiences the complications. With the longer wait, it can take some time to realize the direct cause is the hernia mesh. Lawsuits have been filed for hernia mesh complications that resulted from recalled products or those that have been deemed to be defective. The cost of repair can be quite a financial burden with multiple surgeries and even permanent damage.
Complications from Hernia Mesh
Hernia mesh products have been around and used in hernia repair surgeries since they were first introduced in the 1950s. However, they have not been without some serious complications, which can even be life-threatening. While there are risks for any hernia repair surgery, some of the most common and most serious have resulted from mesh products that have been recalled.
Adhesion from Hernia Mesh Products
One of the most common issues is adhesion from the mesh implanted in the abdomen of the patient. Hernia mesh products are made of a variety of materials, and they may attach to tissue inside. The mesh has a coating which helps prevent the issue, but the coating dissolves while the mesh is often permanent.
The mesh may adhere to the abdominal wall or the intestines or other tissue. It can cause severe pain that won’t go away until the product is removed through surgery. Adhesion can lead to bowel obstruction.
Bowel Obstruction with Hernia Mesh
A bowel obstruction begins with an adhesion to the intestines. It can also migrate where it can entrap the intestines. Symptoms of bowel obstruction include nausea and vomiting. The patient is also unable to pass stool. They will require immediate attention because this is a dangerous condition.
If not treated quickly enough, part of the intestine may need to be removed. Reports from the FDA cite mesh products that have been recalled as a major reason for obstruction.
How Hernia Mesh Causes Bowel Perforation
Recalled products have also been shown to cause perforation in the bowels. This occurs when the mesh punctures the intestine or other area of the abdomen. It may also puncture an organ, creating a life-threatening condition.
Symptoms of a bowel perforation include nausea and vomiting along with severe pain in the abdomen and rigidity of the abdomen – the abdomen feels hard. Bacteria can get into the abdomen from the puncture, which can then lead to sepsis and peritonitis. These conditions may be fatal.
Infection from Hernia Mesh
An infection may result from hernia mesh surgery. Often, the mesh will need to be removed through surgery. Antibiotics can treat minor issues while deep infections are more complicated. Chronic infection may not begin for years after the initial surgery, which can make it more difficult to diagnose.
A person with infection from a hernia mesh product may experience inflammation and fever. They may notice other flu-like symptoms as well.
Migration of the Hernia Mesh
Another complication for hernia mesh surgery is that the product will detach and migrate into other areas of the body. Complications from a migrating mesh can include the following:
- Bowel obstruction
- Bowel perforation
In one case reported to the FDA, an implant detached and migrated to the intestine where it adhered. Surgery was required to remove the mesh along with a portion of the intestine.
There may be pain with migration or the patient may not have any symptoms until other damage occurs.
The hernia mesh product may rip, tear or disintegrate, causing problems. The mesh can rip from the sutures, which often happens if the person lifts something too heavy or overexerts themselves too soon after surgery.
Another issue is if the mesh shrinks, which can cause it to come lose from the sutures in time. A long-term issue is when the mesh erodes and breaks into pieces. The pieces may move around and perforate surrounding tissue.
All of these problems can lead to migration, which can cause other complications. Surgery is often necessary to repair the condition.
Issues with hernia mesh can happen right after surgery, a few weeks or months later or years afterwards. The hernia may rupture again even with the mesh in place. While the product is effective at repairing the hernia, it is not a guarantee.
As with any surgical procedure, there is a risk of these complications even if everything is done correctly. However, there have been numerous recalls of hernia mesh products that increase the risk of problems. It may be related to the materials used or the design of the product. Some products have a higher failure rate than others, and some have been recalled due to their safety issues.
It is important to let a doctor know you’ve had a hernia mesh if you experience symptoms that can be associated with these complications. Often, immediate medical attention is necessary to prevent further damage or health issues. It can be difficult to diagnose a condition related to the mesh correctly.
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